DEF6 IS REQUIRED FOR CONVERGENT EXTENSION MOVEMENTS DURING ZEBRAFISH GASTRULATION DOWNSTREAM OF WNT5B SIGNALING.

Def6 is required for convergent extension movements during zebrafish gastrulation downstream of Wnt5b signaling.

During gastrulation, convergent extension (CE) cell movements are regulated through the non-canonical Wnt signaling Clutch Bag pathway.Wnt signaling results in downstream activation of Rho GTPases that in turn regulate actin cytoskeleton rearrangements essential for co-ordinated CE cell movement.Rho GTPases are bi-molecular switches that are inacti

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Anaesthesia for total hip and knee replacement: A review of patient education materials available online [version 1; peer review: 2 approved]

Background: Patients frequently consult the internet for health information.Our aim was to perform an Internet-based readability and quality control study using recognised quality scoring systems to assess the patient information available online relating to anaesthesia for total hip and knee replacement surgery.Methods: Online patient information

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